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About Staff: FY2005

Division of Humans and the Environment
NISHIBUCHI, Mitsuaki (Professor)
Human-Nature Dynamics

 

Research Interests

The current subject of my study is enteric infections in Southeast Asia, particularly the effect on human activities of bacteria distributed in the aquatic environment. Compared with advanced countries, the countries in Southeast Asia suffer much more from enteric infections and they are the most important of the diseases affecting Southeast Asia. This difference cannot be explained simply by levels of hygiene and medical care such as vaccination and treatment. It might be possible that both natural and human environments in Southeast Asia are suitable for the distribution and propagation of enteric pathogens. It is also possible that the practically borderless movement of humans and materials in Southeast Asia might greatly contribute to the spread and prevalence of these diseases. I have been conducting collaborative research to examine these possibilities and this has developed into a research network. We have gained significant insights into the infections caused by emerging bacterial pathogens, including a new clone of Vibrio parahaemolyticus, Vibrio cholerae O139, Esherichia coli O157 and vancomycin-resistant Enterococcus spp. The information obtained has been exchanged among researchers in the network and also made available to the rest of the world through publication in international journals.

Current research topics:

(1) Dynamics of pathogenic bacteria in the environment
(2) Epidemiology of infectious diseases that originate in Southeast Asia
(3) Elucidation of the features of infectious diseases in Southeast Asia by taking the findings of (1), (2) and cultural and social background into consideration

Research Activities in 2005 Fiscal Year

Publication |  Database |  Field Research |  Joint ResearchProject |  Seminar/Symposium |  Outside Activities |  Academic Association | Award
Publication
  1. Benjamin, P. G.; Gunsalam, J. W.; Radu, S.; Napis, S.; Bakar, F. A.; Beon, M.; Benjamin, A.; Dumba, C. W.; Sengol, S.; Mansur, F.; Jeffrey, R.; Nakaguchi, Y.; and Nishibuchi, M. Sep. 2005. Factors Associated with Emergence and Spread of Cholera Epidemics and Its Control in Sarawak, Malaysia between 1994 and 2003. Southeast Asian Studies 43 (2): 109-140
  1. Nakaguchi, Y.; Okuda, J. ; Mashimo-Matsumoto, C.; Chowdhury, A.; Nishioka, T.; and Nishibuchi, M. 2005. Enteric Infections Spread from Asia to the World: Infection by a New Clone of Vibrio parahaemolyticus(in Japanese). Kagaku-ryoho-no-ryoiki 21(4): 545-549.
  1. Wong, H. C.; Chen, C. H. ; Chung, Y. J. ; Liu, S. H. ; Wang,T. K. ; Lee, C. L.; Chiou, C. S. ; Nishibuchi M.; and Lee, B. K. 2005. Characterization of New O3:K6 Strains and Phylogenetically Related Strains of Vibrio parahaemolyticus Isolated in Taiwan and Other Countries. J. Appl. Microbiol. 98(3):572-580.
  1. Martinez-Urtaza, J.; Simental, L.; Velasco, D.; Depaola, A.; Ishibashi, M.; Nakaguchi, Y.; Nishibuchi, M.; Carrera-Flores, D.; Rey-Alvarez, C.; and Pousa, A. 2005. Pandemic Vibrio parahaemolyticus O3:K6, Europe. Emrging. Infections. Disseases 11(8):1319-1320.
  1. Nishibuchi, M. 2005. Results of the Molecular Epidemiological Analysis of Seafood-borne Pathogens Suggest the Flows of the Pathogens along the People and Food across International Borders in Asia. In Proceedings of the Japan Society for the Promotion of Science and National Research Council of Thailand Core University Program Workshop on Flows and Movements in East Asia., pp. 255-264.
  1. Nishibuchi, M.; and DePaola, A. 2005. Vibrio Species. In , Food-borne Pathogens: Microbiology and Molecular Biology, edited by P. M. Fratamico and A. K. Bhunia, Norfolk, U. K. Horizon Scientific Press.: pp. 251-271.
  1. Tanil, G. B.; S. Radu; M. Nishibuchi; R. A. Rahim; S. Napis; L. Maurice; and J. W. Gunsalam. 2005. Characterization of Vibrio parahaemolyticus isolates from coastal seawater in peninsular Malaysia. Southeast Asian J. Trop. Med. 36(4):940-945.
  1. Gopal, S.; Otta, S. K.; Kumar, S.; Karunasagar, I.; Nishibuchi, M.; and Karunasagar, I. 2005. The Occurrence of Vibrio Species in Tropical Shrimp Culture Environments: Implications for Food Safety. Int. J. Food Microbiol. 102: 151-159.
  1. Nakaguchi, Y.; and Nishibuchi, M. 2005. The Promoter Region rather than Its Downstream Inverted Repeat Sequence Is Responsible for Low-level Transcription of the Thermostable Direct Hemolysin-related Hemolysin (trh) gene of Vibrio parahaemolyticus.Journal of . Bacteriol. 187(5): 1849-1855.